Focused protein degradation is getting explored instead technique in cancer, whereby the natural protein degradation technique is co-opted for therapeutic purposes. Lately created novel molecules called proteolysis-focusing on chimeras (PROTACs) are heterobifunctional molecules with two ligands joined by a linker. One particular ligand binds on the ‘protein of fascination’ (POI) https://www.directivepublications.org/journal-of-clinical-breast-cancer/